Kyushu pitavastatin and pravastatin Intervention trial on Diabetic NEphropathY
- Conditions
- Type 2 diabetic nephropathy with Hypercholesterolemia
- Registration Number
- JPRN-UMIN000001324
- Lead Sponsor
- Kyushu University Graduate School of Medical Science Department of Medicine and Bioregulatory Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 100
Not provided
1."Contraindications""Relative Contraindications""Absolute Contraindications for Coadministration" and "Relative Contraindications for Coadministration" for pitavastatin or pravastatin 2.Patients with hypothyroidism or inherited muscle disorder (muscular dystrophy etc.) and patients with a previous history of drug-induced myopathy 3.Non- diabetic nephropathy 4. Renal dysfunction (s-Cr over 1.5 mg/dl) 5.Urinary tract infection 6.Uncontrolled diabetes, defined as HbA1c>10.0% 7.Malignancy 8. Stroke 9. Heart failure (NYHA Class >= III) or myocardial infarction 10.Angina with symptom 11.Participating in clinical trials or clinical research 12.Judged as unsuitable for participating in this study by the attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in urinary albumin/creatinine ratio,Changes in eGFR
- Secondary Outcome Measures
Name Time Method urinary albumin/creatinine ratio, serum creatinine , Urea nitrogen, serum cystein C, LDL-C,TC,TG,HDL-C,non HDL-C, 8-isoprostane, urinary L-FABP, urinary typeIV collagen