Impact of Probiotics Supplement on the Gut Microbiota in Caesarean-born Infants: an Open-label Single-center Randomized Parallel Controlled Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gut Microbiota
- Sponsor
- Shanghai 10th People's Hospital
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Change in gut microbiota at 14 days between no intervention and experimental group.
- Last Updated
- 4 years ago
Overview
Brief Summary
The purpose of this study is to evaluate the effect of probiotics on the gut microbiota of infants born by cesarean section.
Detailed Description
This study aims to examine the impact of probiotics administration on the gut microbiota of infants born by cesarean section. Birth,14 days and 42 days data will be collected and put into analysis to provide some suggestions on the probiotics use in the clinical for the infants born by cesarean section.
Investigators
Huanlong Qin
Director
Shanghai 10th People's Hospital
Eligibility Criteria
Inclusion Criteria
- •Neonates born by caesarean section
Exclusion Criteria
- •Gestational weeks \<37 Birth weight \<2500g or ≥4000g History of asphyxia anoxia at birth With congenital metabolic diseases or hereditary diseases With gastrointestinal diseases With infectious diseases
Outcomes
Primary Outcomes
Change in gut microbiota at 14 days between no intervention and experimental group.
Time Frame: 14 days
Study the microbiota change of stool samples 14 days between no intervention group and experimental group.
Change in gut microbiota at 42 days between no intervention group and experimental group.
Time Frame: 42 days
Study the microbiota change of stool samples at 42 days between no intervention group and experimental group.
Secondary Outcomes
- Change in gut microbiota at birth between no intervention and experimental group.(birth)