Measurment of Blood Recirculation and Adjustment of vvECMO Blood Flow During Veno-venous Extracoporeal Membrane Oxygenation

Charite University, Berlin, Germany1 site in 1 country21 target enrollmentAugust 13, 2017

ConditionsARDS Extracorporeal Membrane Oxygenation

Overview

Phase: N/A
Intervention: Not specified
Conditions: ARDS
Sponsor: Charite University, Berlin, Germany
Enrollment: 21
Locations: 1
Primary Endpoint: Recirculation of vvECMO blood flow
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

A prospective, observational study will be performed measuring recirculation of blood through a veno-venous Extracoporeal Membrane Oxygenation (vvECMO) in patients with acute respiratory distress syndrome (ARDS) on vvECMO. ECMO blood flow will be adjusted with respect to recirculation.

Registry

clinicaltrials.gov

Start Date

August 13, 2017

End Date

August 9, 2018

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Charite University, Berlin, Germany

Responsible Party

Principal Investigator

Steffen Weber-Carstens

Prof. Dr. med.

Charite University, Berlin, Germany

Eligibility Criteria

Inclusion Criteria

•patients aged 18 years or older
•veno-venous ECMO

Exclusion Criteria

•age \< 18 years
•hemodynamic instability during measurement of recirculation
•pregnancy
•inability to obtain patient's consent or consent of legal guardian

Outcomes

Primary Outcomes

Recirculation of vvECMO blood flow

Time Frame: Once within first week after ICU admission during 4 hours

Amount of ECMO blood flow recirculating through the vvECMO circuit

Secondary Outcomes

Reduction of vvECMO blood flow(Once within first week after ICU admission during 4 hours)
Arterial blood oxygen content after reduction of vvECMO blood flow(Once within first week after ICU admission during 4 hours)