NCT01842412已完成不适用
The Initial Effect of Training on Mitochondrial Function in Patients With Intermittent Claudication
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Mitochondrial function
研究概览
简要总结
The hypothesis of this study is that one bout of leg exercise gives acute qualitative changes in mitochondrial function in claudication. Final purpose is to determine the optimal exercise frequency in treatment of claudication.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •A history of any type of uni- or bilateral exertion leg pain.
- •A maximal claudication distance that is less than 300 meter
- •Diagnosed with intermittent claudication secondary to vascular insufficiency
- •An ankle-brachial index between 0.4 and 0.
- •Lives in Trondheim
排除标准
- •Diagnosed with critical limb ischemia
- •ankle-brachial index > 0.90 or < 0.4
- •Limited exercise tolerance
- •Warfarin or heparin usage
- •Diabetes mellitus
- •Underwent a vascular intervention in the last 3 months
- •Active cancer, renal- or liver disease.
结局指标
主要结局
Mitochondrial function
时间窗: One day
respirometry
次要结局
未报告次要终点
研究者
研究点 (1)
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