Intravenous Cannulation In Children During Sevoflurane Induction

Not Applicable

Completed

• Conditions: Intravenous Cannulation; Sevoflurane Induction; Child
• Interventions: Other: Intravenous Cannulation (iv placement)

• Registration Number: NCT03851692
• Lead Sponsor: University Hospital Fattouma Bourguiba

Brief Summary

The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2). The aim of the investigator's study is to determine whether one should make iv attempts during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia

Detailed Description

the investigators conducted a prospective randomized study, after obtaining Institutional review board approval, which didn't require written parental consent. Children age 1-12 years, undergoing elective general anesthesia via an inhalation induction were randomized to one of three groups of 30 patients each one, for iv placement, either 60s (group E), 90 or 120 s (group L) following loss of lid reflex. Movement on iv placement and incidence of laryngospasm were determined. Difficulty with iv placement was also recorded. Statistical analysis included contingency testing, ANOVA, and non parametric testing. A P-value \<0.05 was considered significant.

Study Timeline

• Study Start: 2016-08-01
• Primary Completion: 2016-12-31
• Study Completion: 2016-12-31
• Study First Submitted: 2018-10-27
• Status Verified: 2019-02
• Study First Submitted QC: 2019-02-20
• Last Update Submitted: 2019-02-20
• Study First Posted: 2019-02-22
• Last Update Posted: 2019-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• ASA I, II
• Age from 1 to 12 years old
• Ambulatory surgery under general anesthesia.

Exclusion Criteria

• Age <1 year or> 12 years
• non-ambulatory surgery,
• contraindication for induction with sevoflurane

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
60s (group E)	Intravenous Cannulation (iv placement)	Intravenous cannulation was released either 60 s following loss of lid reflex in group E
90 or 120 s (groupe L)	Intravenous Cannulation (iv placement)	Intravenous cannulation was released either 90 or 120 s following loss of lid reflex in group L

Primary Outcome Measures

Name	Time	Method
laryngospasm	Time From Intravenous Cannulation to patient extubation	The incidence of laryngospasm
Movement on iv placement	In the first 5 min after the anesthesic induction with sevoflurane	Number of children who presented movement on iv placement