A randomized trial comparing the ER-cap technique and the multiband mucosectomy technique for piecemeal endoscopic resection of early Barrett neoplasia.

Recruiting

• Conditions: Barrett esophagus; Barrett oesophagus; Barrett neoplasia; high-grade dysplasia; early cancer; endoscopic resection; ER-cap technique; multiband mucosectomy technique

• Registration Number: NL-OMON25855
• Lead Sponsor: Academic Medical Center, Department of Gastroenterology and Hepatology.

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

1. BE with biopsy proven high-grade dysplasia (HGD) and/or early cancer (EC);

2. In case of visible lesions: type 0-IIa, 0-IIb, 0-IIc, or combinations of these types;

Exclusion Criteria

1. Lesion with suspicion on submucosal invasion;

2. Unable to give informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- Rate of radically resected lesions; <br /><br>- Number and severity of complications.

Secondary Outcome Measures

Name	Time	Method
- Time per procedure;<br /><br>- Number of resected pieces per procedure,<br /><br>- Costs of disposables per procedure;<br /><br>- Maximum diameter of resected specimens;<br /><br>- Maximum thickness of submucosa in resected specimens.<br />