Before surgery intranasal dexmedetomidine administration and it’s effect on spinal anaesthesia in leg orthopaedic surgeries
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/02/040313
- Lead Sponsor
- AIIMS RAIPUR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients aged 18-65 years
Study includes both male and female
All orthopedic surgeries under spinal anesthesia
Signed informed consent given by legally authorized representative
ASA Grade 1 and 2
Exclusion Criteria
Non-compliant Patients
Allergy to the drug
Patients on Beta blockers or Anti-hypertensive drugs
Recent history of use of other sedatives and anxiolytics
Patients on antidepressants
Recent history of upper respiratory tract infection/ history of bronchial asthma
Presence of obvious nasal mass
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Potentiation of spinal effect with intranasal dexmedetomidine. <br/ ><br>Improved analgesia effect with intranasal dexmedetomidine. <br/ ><br>Satisfactory sedation. <br/ ><br>Reduced need of Opioids in the post operative period. <br/ ><br>Timepoint: Six hours <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. To assess the effect of pre operative intranasal dexmedetomidine in causing intraoperative and postoperative analgesia. <br/ ><br>2. To assess the effect of pre operative intranasal dexmedetomidine as sedative intraoperatively/post-operatively by RASS scale. <br/ ><br>3. To look for any adverse effects following intranasal administration of the drug. <br/ ><br>4. The need for rescue analgesia <br/ ><br>Timepoint: 6 hours