Factors predicting intraoperative inoperability in radiologically resectable gallbladder malignancies
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 333
- 试验地点
- 1
研究概览
简要总结
Study Title:- Factors predicting intraoperative inoperability in radiologically resectable gallbladder malignancies
Type of Study:- Retrospective Observational Study
Gallbladder cancer (GBC) is an aggressive malignancy in which surgical resection offers the best chance of long-term survival. Although preoperative evaluation using tumor markers, CT/PET-CECT and staging laparoscopy suggests resectability, a subset of patients (approximately 15–20%) are found to be inoperable during surgery. Inoperability may result from peritoneal disease, liver metastases, positive peritoneal cytology, inter-aortocaval lymph node involvement or extensive local tumor spread. Identifying preoperative and intraoperative predictive factors allows better patient selection, improves surgical decision-making and may reduce non-therapeutic laparotomies.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Any patient with GBC deemed inoperable on staging laparoscopy and exploratory laparotomy (for early GBC, locally advanced GBC and incidentally detected GBC.
- •iGBC ) will be included in the inoperable group. All patients operated for radical cholecystectomy for gallbladder malignancy (early GBC, locally advanced GBC and incidentally detected GBC) will be included in the operable group.
排除标准
- •Operated gallbladder patients for non-malignant causes •Final histopathology for gallbladder does not show malignancy.
研究者
Dr Shraddha Padkar
Tata Memorial Hospital