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Clinical Trials/CTRI/2020/11/029241
CTRI/2020/11/029241Not yet recruitingPhase 3

Comparative evaluation of Dexmedetomidine nebulisation and Ketamine nebulisation as an adjuvant to Lignocaine for awake fiberoptic intubation.

King Georges Medical University1 site in 1 country60 target enrollmentStarted: November 20, 2020Last updated:
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Trial Snapshot

Phase
Phase 3
Status
Not yet recruiting
Sponsor
Enrollment
60
Locations
1
Primary Endpoint
to assess the ease of intubation
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

difficulty in airway management during anaesthesia can lead to severe anaesthesia related morbidity and mortality. awake intubation now has become one of the recommended modality to manage airway that is expected to be difficult. fibreoptic bronchoscopy is a relatively safer method used now for the management of the same.

comparasion between dexmedetomedine and ketamine nebulisation as an adjuvant to lignocaine for awake fiberoptic intubation could bring new insight in the area of awake intubations.

Study Design

Study Type
Interventional
Allocation
Computer generated randomization
Masking
Participant and Investigator Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •Patients with American Society of Anaesthesiology grading of 1 and
  • •Patients having Mallampati grading of 3 and 4 and mouth opening less than 2 finger and also patients in whom neck extension is contraindicated.

Exclusion Criteria

  • •patients with any type of AV block, bradycardia, hypotension, ventricular dysfunction, heart failure, coronary disease.
  • •patients with nasal pathology and recent epistaxis.
  • •allergy to drugs being used in the study patients not giving consent.

Outcomes

Primary Outcomes

to assess the ease of intubation

Time Frame: to assess the ease of intubation using glottic score and cough score during bronchoscopy.

Secondary Outcomes

  • to assess the degree of sedation between two groups using Ramsay sedation score.(to assess the hemodynamic parameters of patient preoperatively, during intubation and during the intra operative period.)

Investigators

Sponsor
King Georges Medical University
Sponsor Class
Government medical college

Study Sites (1)

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