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临床试验/CTRI/2025/11/097782
CTRI/2025/11/097782尚未招募不适用

Impact of BAriatric Surgery on Body COmposition, Basal Metabolic Rates and Muscle functions in Morbid Obese Patient: A Prospective Observational Study

AIIMS Bhubaneswar1 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2025年12月2日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
21
试验地点
1

研究概览

简要总结

Prospective Observational Cohort study, In this study, morbidly obese patients undergoing bariatric surgery will be assessed at baseline and followed by 3rd  and 6 months to evaluate various physiological and biochemical changes. Anthropometric measurements including height, weight, BMI, and waist-hip ratio will be recorded. Body composition will be assessed using Bioelectrical Impedance Analysis (BIA), which will provide data on percentage body fat (PBF), segmental muscle mass (SMM), segmental fat mass (SFM), and skeletal muscle index (SMI). Basal metabolic rate (BMR) will also be measured through BIA. Muscle strength will be evaluated using a hand grip dynamometer, while muscle performance will be assessed via gait speed using the 6-meter walk test. Inflammatory markers such as high-sensitivity C-reactive protein (HsCRP), erythrocyte sedimentation rate (ESR), and interleukin-6 (IL-6) will be analyzed. Additionally, metabolic parameters including thyroid-stimulating hormone (TSH), fasting and postprandial blood glucose, HbA1c, and lipid profile will be measured to understand the systemic effects of the surgery.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • BMI more than 35 with or without obesity-related comorbidities Planned for Bariatric and Metabolic Surgery.

排除标准

  • Known endocrine disorders (Cushing’s and Untreated hypothyroidism History of prior bariatric surgery Inability to comply with follow-up Schedules to follow-up before 3 months post-treatment.

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Prakash Kumar Sasmal

AIIMS bhubaneswar

研究点 (1)

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