A prospective study on reactive hypoglycaemia following bariatric surgery.

The University of Adelaide0 个研究点目标入组 30 人开始时间: 2022年4月26日最近更新: 2022年5月30日

适应症

试验速览

暂无简介。

•Males and females with or without diabetes who are planned to have Roux-en-Y gastric bypass or one anastomosis gastric bypass.

•Use of any medication that may influence gastrointestinal motor function, body weight or appetite (glucagon-like peptide 1 receptor agonists, dipeptidyl peptidase 4 inhibitors, opiates, anticholinergics, levodopa, clonidine, nitrates, phosphodiesterase type 5 inhibitors, sumatriptan, metoclopramide, domperidone, prucalopride, or erythromycin)
•Evidence of drug abuse, consumption of more than 20 g alcohol per day or an active smoking history
•History of chronic gastrointestinal disease (inflammatory bowel disease, coeliac disease) or prior gastrointestinal surgery (other than other than bariatric surgery, uncomplicated appendicectomy or cholecystectomy)
•History of epilepsy
•History of severe respiratory, cardiovascular, hepatic and/or renal disease
•Impaired renal (as assessed by calculated creatinine clearance < 90 mL/min), iron status, or liver function tests outside the following ranges:
•-Alanine aminotransferase (ALT) >3x ULN
•-Aspartate transaminase (AST) >3x ULN
•-Alkaline phosphatase (ALP) >3x ULN
•-Bilirubin >24 mmol/L
•-Ferritin <15 ng/mL (Females), <30 ng/mL (Males)
•-Haemoglobin <115 g/L (Females), <130 g/L (Males)
•Donation of blood within the previous 3 months
•Participation in any other research studies within the previous 3 months that requires blood sampling or exposure to radiation
•Inability to give informed consent
•Female participants who are pregnant or planning for pregnancy, or are lactating
•Vegetarian

发起方