nderstanding the effects of weight loss/improvements in obesity related co-morbidities on sperm function.

Robinson Research Institute, University of Adelaide0 个研究点目标入组 216 人开始时间: 2017年3月1日最近更新: 2019年7月15日

适应症

试验速览

暂无简介。

•Inclusion Criteria
•(1) BMI >30 kg/m2 and a waist circumferences of >102cm. These are the current standard criteria for categorising obesity. A number of studies assessing male obesity and fertility have used waist circumference in conjunction with BMI, as waist circumference in humans has been determined to be a better indicator for cardio metabolic disease risk.
•(2) Males aged 18-40years. ROS the primary outcome is not altered in this age range. There are also little reported changes to other sperm parameters to be measured in this age range.
•(3) At recruitment, patient is on a participating clinic’s waiting list to undergo a first-time SG, ABG or RYGB. To ensure participants in the study are not having a revision or conversion which may confound results.

•Exclusion Criteria (known con-founders)
•(1) Males who have had vasectomies or vasectomy reversals.
•(2) Males with un-descendent testes, suspected pathologies related to fertility (i.e. varicoceles) or known genetic disorders that effect weight and fertility (i.e. Klinefelter's Syndrome, Prader-Willi or Larence-Moon-Bardet-Biedel).
•(3) Males diagnosed with azoospermia at initial assessment. During the study period any results with implications for future or current fertility or for general wellbeing will be noted, and results will be sent to participant’s general practitioners, with the option for participants to be referred to fertility specialists.

发起方

Robinson Research Institute, University of Adelaide