Objective Vestibular Evaluation & Rehabilitation With Intratympanic Dexamethasone and Gentamicin in Meniere's Disease
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- Vestibular Rehabilitation
研究概览
简要总结
Intractable symptoms of Meniere's disease will be treated with intratympanic steroids.
At the same time intratympanic dexamethasone will be used to rescue hearing
详细描述
For Alleviation of Intractable symptoms of Meniere's disease will be treated with intratympanic steroids. Measured with pre and post therapy vestibular severity index.
At the same time intratympanic dexamethasone will be used to rescue hearing measured with speech reception threshold and speech discrimination threshold
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
For Alleviation of Intractable symptoms of Meniere's disease will be treated with intratympanic steroids. Measured with pre and post therapy vestibular severity index.
At the same time intratympanic dexamethasone will be used to rescue hearing measured with speech reception threshold and speech discrimination threshold
入排标准
- 年龄范围
- 24 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients of unilateral Meniere's disease with severe vestibular symptoms
排除标准
- •Bilateral disease, operated cases
研究组 & 干预措施
Vestibular severity index improvement
Improvement in vestibular symptoms with intratympanic gentamicin
干预措施: Gentamicin (Drug)
Vestibular severity index improvement
Improvement in vestibular symptoms with intratympanic gentamicin
干预措施: Dexamethasone (Drug)
结局指标
主要结局
Vestibular Rehabilitation
时间窗: Three months
Improvement in vestibular severity index
次要结局
未报告次要终点
研究者
Dr Zeeshan Ayub
Associate Professor ENT
Combined Military Hospital Quetta