Objective Vestibular Evaluation & Rehabilitation With Intratympanic Dexamethasone and Gentamicin in Meniere's Disease
Overview
- Phase
- Not Applicable
- Intervention
- Gentamicin
- Conditions
- Vestibular Disorder Preservation
- Sponsor
- Combined Military Hospital Quetta
- Enrollment
- 93
- Locations
- 1
- Primary Endpoint
- Vestibular Rehabilitation
- Last Updated
- 4 years ago
Overview
Brief Summary
Intractable symptoms of Meniere's disease will be treated with intratympanic steroids.
At the same time intratympanic dexamethasone will be used to rescue hearing
Detailed Description
For Alleviation of Intractable symptoms of Meniere's disease will be treated with intratympanic steroids. Measured with pre and post therapy vestibular severity index. At the same time intratympanic dexamethasone will be used to rescue hearing measured with speech reception threshold and speech discrimination threshold
Investigators
Dr Zeeshan Ayub
Associate Professor ENT
Combined Military Hospital Quetta
Eligibility Criteria
Inclusion Criteria
- •All patients of unilateral Meniere's disease with severe vestibular symptoms
Exclusion Criteria
- •Bilateral disease, operated cases
Arms & Interventions
Vestibular severity index improvement
Improvement in vestibular symptoms with intratympanic gentamicin
Intervention: Gentamicin
Vestibular severity index improvement
Improvement in vestibular symptoms with intratympanic gentamicin
Intervention: Dexamethasone
Outcomes
Primary Outcomes
Vestibular Rehabilitation
Time Frame: Three months
Improvement in vestibular severity index