A Clinical trail comparing two drugs - lignocaine and dexmedetomidine in maintaining stable heart rate and blood pressure during laparoscopic surgeries.
Not Applicable
Completed
- Conditions
- Health Condition 1: K810- Acute cholecystitisHealth Condition 2: N832- Other and unspecified ovarian cystsHealth Condition 3: K36- Other appendicitis
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 81
Inclusion Criteria
Patients belonging to America Society of Anaesthesiologists (ASA) 1 and ASA 2 physical status.
Exclusion Criteria
Emergency surgeries. Patients with reduced autonomic control like elderly patient, uncontrolled diabetic patient. Patients with pre operative hypotension, bradycardia, dysrhythmia, severe cardiac diseases, complete heart block. Patients on treatment with beta blockers. Patients with hepatic or renal dysfunction. Obese patients, patients with history of obstructive sleep apnea. Pregnant patients. Patients with allergies to any component of the drugs being used. Patients with high risk of bleeding and high chance of laparoscopic surgery being converted open surgery.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure and compare the mean arterial pressure in the three group of patients (lignocaine group, Dexmedetomidine group, Normal saline group)Timepoint: At various time points durging the surgery.
- Secondary Outcome Measures
Name Time Method To compare intraoperative opioid requirements in the three group of patients (lignocaine group, Dexmedetomidine group, Normal saline group)Timepoint: Intraoperative duration;To compare the postoperative pain scores using VNRS in the three group of patients (lignocaine group, Dexmedetomidine group, Normal saline group)Timepoint: Postoperative period;To measure and compare the hemodynamic parameters (heart rate, systolic blood pressure and diastolic blood pressure) in the three group of patients (lignocaine group, Dexmedetomidine group, Normal saline group)Timepoint: At various time points durging the surgery.