Treatment Of Endometrial Hyperplasia
Phase 3
Recruiting
- Conditions
- Endometrial Hyperplasia.Endometrial hyperplasiaN85.0
- Registration Number
- IRCT20221015056181N1
- Lead Sponsor
- Ghoum University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 134
Inclusion Criteria
Having a pathological diagnosis of EEC or AEH
Desire to preserve fertility
Not having suspicious signs of tissue invasion
No hormonal treatment in the last 6 months
Obtain informed consent
Age 18 to 45 years
Exclusion Criteria
Contraindications for metformin
Contraindications for progesterone (megestrol)
Use of metformin in the last six months
Blood sugar less than 60 or more than 200 mg/dL
Using oral contraceptives or estrogen or progesterone
Alcohol addiction
Severe infection
Severe chronic disease (impairment of heart, liver, lung or kidney function)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endometrial Hyperplasia. Timepoint: Examination of endometrial hyperplasia after 3 weeks of treatment. Method of measurement: Endometrial biopsy.
- Secondary Outcome Measures
Name Time Method