a clinical trial to study the effect of metformin and its correlation with vitamin d levels in patients with pulmonary fibrosis

Phase 2

• Conditions: Health Condition 1: J841- Other interstitial pulmonary diseases with fibrosis

• Registration Number: CTRI/2023/10/059325
• Lead Sponsor: AIIMS New Delhi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 19 December 2023

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Age more than 40 years
2.Patients of pulmonary fibrosis diagnosed, according to most recent American Thoracic Society (ATS), European Respiratory Society (ERS), Japanese Respiratory Society (JRS), Latin American Thoracic Association (ALAT) guidelines by High-Resolution Computerized Tomography (HRCT) pattern, and/ or, if available, surgical lung biopsy pattern.

Exclusion Criteria

1. Patients who are not willing to participate and will not provide informed consent.

2. Pregnant and lactating women

3. Patients with Diabetes

4. Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT) > 1.5 x Upper Limit of Normal (ULN)

5. Bilirubin > 1.5 x ULN;

6. Airway obstruction (i.e., pre-bronchodilator FEV1/FVC < 0.7);

7. Patient likely to have lung transplantation during the study (being on transplantation list is acceptable for participation);

8. Myocardial infarction within 6 months;

9. Unstable angina within 1 month

Study & Design

• Study Type: Interventional
• Study Design: Not specified