Acute Pain Episodes in Patients Under Opioid Maintenance Therapy : Clinical Management and Long Term Effects

Completed

• Conditions: Acute Pain

• Registration Number: NCT00738036
• Lead Sponsor: University Hospital, Toulouse

Brief Summary

To define a rational pharmacological management of pain for the subjects under opioid maintenance therapy (methadone or buprenorphine), it is first of all necessary to estimate the efficiency of the current practices on pain management as well as their potentially noxious consequences, in particular on the long term opioid maintenance therapy.

The objective of the study is to compare the efficiency of the opioid maintenance therapy according to the arisen of an acute painful phenomenon requiring an analgesic management for these patients. At first, this work will allow to determine the results on acute pain of the current practices for these patients. The comparison of the long term consequences on opioid maintenance therapy between the patients that presented an acute painful phenomenon and the control patients should help to improve acute pain management for these patients while limiting the risk of relapse in the abused consumption of psychoactive substances.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-04
• Study First Submitted: 2008-08-19
• Study First Submitted QC: 2008-08-19
• Study First Posted: 2008-08-20
• Primary Completion: 2009-11
• Study Completion: 2009-11
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-10
• Last Update Posted: 2017-05-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 151

Inclusion Criteria

• Patients aged 18 or more.
• Patients under opioid maintenance therapy (buprenorphine or methadone)
• Patients treated by the same drug (buprenorphine or methadone) since at least 3 months

Exclusion Criteria

• Refusal of the patient to take part in the study
• Absence of possible follow-up

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Retention rate under buprenorphine or methadone treatment defined as the percentage of patients still under treatment during the follow-up	1, 3, 6 and 12 months

Secondary Outcome Measures

Name	Time	Method
pain, anxiety, drugs, alcohol and other substances abuse and dependence, drug prescription (included for pain treatment and opioid maintenance)	1, 3, 6 and 12 months

Trial Locations

Locations (1)

University Hospital Toulouse; 🇫🇷 Toulouse, France