Effective Dose of Remimazolam for Sedation in Patients Undergoing Lower Extremity Surgery under Spinal Anesthesia
Not Applicable
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0006828
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
*Age: Adults aged 19 to 65
*Patients with ASA PS 1-3
*Patients receiving sedation using remimazolam among patients undergoing lower extremity surgery under spinal anesthesia
Exclusion Criteria
*Patients who refused to participate in the study
* Patients with hypersensitivity to benzodiazepines or flumazenil
*Patients with severe liver disease
*Patients with communication difficulties
*Patients with severe obstructive sleep apnea or other diseases expected to difficult airway
*Patients who are contraindicated in spinal anesthesia
*Patients who are judged unsuitable for participation by medical staff for other reasons
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method A sustained infusion dose of remimazolam that maintains a MOAA/S scale of 3 or less
- Secondary Outcome Measures
Name Time Method respiratory depression;The estimated effect site concentration of that maintains a MOAA/S scale of 3 or less;Blood pressure;Heart rate