Preventing Excessive Weight Gain and Maternal and Infant Fat Accretion by Increasing Fiber Intake and Changing the Maternal Microbiome During Pregnancy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 51
- 试验地点
- 2
- 主要终点
- Maternal Weight Changes
研究概览
简要总结
The purpose of this study is to learn if consuming a high fiber diet will reduce gestational weight gain and maternal and infant fat accretion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pre-pregnancy BMI 18.5 - 45.0 kg/m2
排除标准
- •Comsuming more than 20 g/day of fiber
- •No phone and internet access
- •Pre-gestational diabetes
- •Diagnosed with diabetes
- •Pre-eclampsia
- •Hypertension
- •Other metabolic abnormalities
- •Heart disease
- •Drug abuse
- •Recent antibiotic use
- •Pregnancies of multiples
结局指标
主要结局
Maternal Weight Changes
时间窗: Baseline through 2-mounths postpartum
Assess weight change between groups
Maternal Fat Accretion Changes
时间窗: Baseline through 2-mounths postpartum
Assess fat accretion change between groups using the Selinger four-compartment model
Identify Changes in Fiber Intake
时间窗: Baseline through 2-months postpartum
Compare fiber intake between groups by using 24-hour dietary recalls
Identify Changes in Dietary Quality
时间窗: Baseline through 2-months postpartum
Compare dietary quality between groups using the Alternative Healthy Eating Index (AHEI) scoring ranges from 0 to 100 (higher score means a better diet quality).
次要结局
- Maternal Weight(2-months through 12-months postpartum)
- Infant Fat Accrual(Birth to 12-month old)
- Maternal Fat Accretion(2-months through 12-months postpartum)
- Dietary Fiber Intake(2-months through 12-months postpartum)
- Dietary Quality(2-months through 12-months postpartum)