Evaluation of a New MR Pulse Sequence to Quantify Liver Iron Concentration
Completed
- Conditions
- Hemochromatosis
- Registration Number
- NCT00587535
- Lead Sponsor
- Mayo Clinic
- Brief Summary
The purpose of this study is to determine if a new MR pulse sequence is accurate in determining how much iron is in the liver.
- Detailed Description
Quantification of liver iron requires liver biopsy and histological assessment. New rapid MR techniques allow determination of liver relaxation times that can be altered with increasing iron deposition. The purpose of this study is to compare the results obtained with MRI to liver biopsy and iron quantification in patients undergoing liver biopsy in the setting of hemochromatosis.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
- Undergoing liver biopsy for suspected or known hemochromatosis
- Undergoing liver biopsy for living-related liver donation evaluation
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Exclusion Criteria
- Contraindication to MRI
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Accuracy of MR in quantifying liver iron one time point
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mayo Clinic
🇺🇸Rochester, Minnesota, United States