Continuous Saphenous Nerve Block for Total Knee Arthroplasty

Not Applicable

Completed

• Conditions: Pain, Postoperative
• Interventions: Procedure: continuous saphenous nerve block; Procedure: Saline boluses in nerve catheter

• Registration Number: NCT01332045
• Lead Sponsor: Henning Lykke Andersen

Brief Summary

Our study will compare the use of continuous saphenous nerve block performed at the adductor canal in addition to Local Infiltration Analgesia (LIA) versus a Sham block in addition to LIA for total knee replacement. The investigators hypothesize that the saphenous nerve block performed at the level of the adductor canal in addition to LIA provides better pain relief than the LIA alone without significantly compromising muscle strength and physiotherapy, enabling patients to mobilize early with reduced opioid consumption and les side effects.

The investigators will enroll a total of 40 patients (20 patients will receive continuous saphenous nerve block in addition to LIA and 20 will receive the sham block and LIA). Until discharge, the investigators will record patients' pain scores, opioid consumption, side effects and physical therapy progress.

If our study proves that the continuous saphenous nerve block in addition to LIA can effectively reduce postoperative pain scores to an acceptable level with better physical therapy progress and less opioid consumption, it could be seen as a more attractive alternative to LIA alone or other traditionally used methods of postoperative pain control that compromises muscle strength and physiotherapy.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-04
• Study First Submitted: 2011-04-07
• Study First Submitted QC: 2011-04-07
• Study First Posted: 2011-04-08
• Status Verified: 2012-01
• Primary Completion: 2012-01
• Study Completion: 2012-01
• Last Update Submitted: 2012-01-18
• Last Update Posted: 2012-01-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• ASA I-III
• Age: 40-75
• Unilateral TKA
• Use of Spinal anesthesia

Exclusion Criteria

• Allergy to any of the study medications
• Intolerance to morphine
• Contraindication to a spinal anesthetic
• Intraoperative use of any volatile anesthetic
• Chronic opioid use
• ASA Class 4-5
• Rheumatoid arthritis or Diabetes mellitus with neuropathy
• Liver or kidney failure
• BMI above 40
• Severe COPD

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Continuous saphenous nerve block	continuous saphenous nerve block	Postoperative intermittent boluses of 15 Ml Ropivacaine 7,5 mg/Ml every 12 hours for three days
Saline boluses in nerve catheter	Saline boluses in nerve catheter	A nerve catheter will be placed in the adductor canal using saline instead of Ropivacaine for intermittent boluses.

Primary Outcome Measures

Name	Time	Method
Pain scores	3 days postoperative	VAS pain scores

Secondary Outcome Measures

Name	Time	Method
physical therapy progress	3 days postoperative
Opioid consumption	3 days postoperative

Trial Locations

Locations (1)

Anaestesiafdelingen, Frederiksberg Hospital; 🇩🇰 Frederiksberg, Denmark