Verband tussen dieetsamenstelling micoörganismen in het maagdarmkanaal en de gevoeligheid voor pinda kinderen met een pinda allergie. Een pilot studie
Completed
- Conditions
- Children with confirmed or suspect peanut allergy in whom an oral food challenge with peanut is performed
- Registration Number
- NL-OMON24764
- Lead Sponsor
- OLVG
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Inclusion criteria for dietary analysis and quality of life scores
•All children eligible for an open or double-blind peanut challenge.
Exclusion Criteria
Exclusion criteria
•Children not eligible for peanut challenge, according to protocol
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relationship between composition of the diet, composition of the microbiome and the reactive dose (threshold levels) in positive Open peanut challenge or DBPCFC with peanut.
- Secondary Outcome Measures
Name Time Method In children, while on a peanut free diet, with a negative or positive peanut challenge:<br /><br>1.Intake of foods, food groups, macro- and micronutrients while on peanut free diet<br /><br>2.Quality of life scores<br /><br>3.Amount of food-derived microbes in diet<br>In children, while on a peanut free diet, with a positive peanut challenge<br /><br>4.Microbiome characterization of oral cavity<br /><br>5.Microbiome characterization of the gut.<br /><br>