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临床试验/NCT06065956
NCT06065956已完成1 期

Comparison of Hemodynamic Changes With Morphine Versus Esmolol as an Adjuvant Agent During Induction of Anaesthesia

Pakistan Navy Station Shifa Hospital1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2022年8月28日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
110
试验地点
1
主要终点
Blood pressure

研究概览

简要总结

Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia

详细描述

Comparing hemodynamic profile of patients during induction of General Anesthesia with intravenous morphine as an adjuvant drug versus Intravenous esmolol as an adjuvant agent,My aim is to study which drug has superior hemodynamic profile in terms of hemodynamic stability of patient requiring General Anesthesia.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
25 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • ASA 2 patients presenting for elective surgery.

排除标准

  • Patients having major cardiac disease.
  • Metastatic disease.
  • Pregnant females.
  • Those unwilling to be part of study.

研究组 & 干预措施

Morphine group

Experimental

Half of participants will be comprising of morphine group

干预措施: Intravenous morphine (Drug)

Esmolol group

Experimental

Half of participants will be comprising of esmolol group

干预措施: Intravenous morphine (Drug)

结局指标

主要结局

Blood pressure

时间窗: 06 months

Change in blood pressure between baseline value and post Intubation value will be measured in millimeter of mercury (mmHg).

Pulse rate

时间窗: 06 months

Change in pulse rate between baseline value and post intubation value will be measured per minute.

次要结局

未报告次要终点

研究者

发起方
Pakistan Navy Station Shifa Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kenan Anwar Khan

FCPS 2 Registrar in Anaesthesiology

Pakistan Navy Station Shifa Hospital

研究点 (1)

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