The effects of filaggrin deficiency on sensitization patterns, severity and quality of life in patients with atopic eczema

• Conditions: dermatitis; 10014982; eczema

• Registration Number: NL-OMON35846
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Patient has been diagnosed with atopic eczema by attending dermatologist

Exclusion Criteria

Patient is not willing to participate
Patient does not speak or read Dutch
Patient is younger than 18 years of age
Patient can not be instructed

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameter is the prevalence of sensitisation to specific inhalant<br /><br>allergens in correlation to filaggrin deficiency.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are the scores on symptom based and quality of life<br /><br>questionnaires and Raman-spectral variations, reflecting variations in<br /><br>molecular composition of the skin in AD.<br /><br></p><br>