An Experimental Study on the effect of biotin on Measurement of FT3, FT4 and TSH in healthy adults

Phase 2

Completed

• Conditions: Healthy Adults; Biotin, Thyroid interference, Discordance of Thyroid function test

• Registration Number: TCTR20240411004
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2024-01-30
• Study Start: 2024-04-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Healthy Adult without underlying disease

Exclusion Criteria

1. History of Allergy to Biotin
2. Pregnancy
3. Breast Feeding
4. Abnormal Thyroid function test or History of Thyroid disease
5. Taking Weight loss supplement
6. Taking Medication that contain Thyroid hormone, Biotin, and Medication that interfere thyroid function test such as amiodarone, carbamazepine within 1 month
7. Taking Supplement, Vitamin within 1 month
8. Smoking
9. History of Severe illness or admitted in hospital within 2 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in FT3, FT4, TSH Before and After taking Biotin At the beginning of study, Day 7, Day 14 ng/d

Secondary Outcome Measures

Name	Time	Method
Comparison of percentage of FT3, FT4, TSH blood test results that were disturbed by Biotin between Beckman Coulter DXI800 and Cobas Elecsys e801. At the beginning of study, Day 7, Day 14 ng/d