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Effectiveness of botulinum toxin injection into masseter muscle to lower face appearance and masticatory functio

Phase 1
Conditions
Healthy human volunteers and no history of the botulinum toxin injection into masseter muscle within 1 year
Botulinum toxin, Masseter, 3D Face scan, Questionnaires
Registration Number
TCTR20240617001
Lead Sponsor
Mahidol university
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
15
Inclusion Criteria

1. Healthy volunteer
2. Any sexual, age more than 20 years old
3. Able to read, write and understand Thai language
4. No history of administering botulinum toxin type A into masseter
muscle within the last 1 year

Exclusion Criteria

1. History of botulinum toxin allergy
2. Infection at the injected area
3. Patients with neuromuscular disorders (e.g., Myasthenia gravis)
4. Pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ower face volume (cm3) 0, 4, 8, 12 weeks Soft tissue volume measurement by program
Secondary Outcome Measures
NameTimeMethod
Patient satisfaction with lower face and jawline 0, 4, 8, 12 weeks Face-Q questionnaires score
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