Long-Term Outcomes in the Treatment of Infantile and Acquired Esotropia With Botulinum Toxin
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 164
- 试验地点
- 1
- 主要终点
- Degree of motor alignment, recurrence rate, incidence of stereopsis, and dissociated vertical deviation along with complications.
研究概览
简要总结
To investigate long-term treatment outcomes of patients receiving botulinum toxin A therapy for infantile and acquired esotropia.
详细描述
Participants: 164 patients with infantile esotropia and 89 patients with acquired esotropia.
Methods: Patients were injected with botulinum toxin into two medial rectus muscles and followed from 1992 to 2005. Patients were evaluated at 1 week, 2, 6 and 12 months, and then yearly post-injection.
Main Outcome Measures: Degree of motor alignment, recurrence rate, incidence of stereopsis, and dissociated vertical deviation along with complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Day 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •infantile esotropia and acquired esotropia
排除标准
- •exotropia, high AC/A ratio accommodative esotropia, patients with neurological deficit including cerebral palsy, Down syndrome and mental retardation, and ocular anomalies including retinopathy of prematurity. Patients lost to follow-up at 6 months or less after the last injection were also excluded.
结局指标
主要结局
Degree of motor alignment, recurrence rate, incidence of stereopsis, and dissociated vertical deviation along with complications.
时间窗: Before treatment, weekly after the treatment, and monthly after motor alignment
次要结局
未报告次要终点