Effects of Dexamethasone on the prevention of elevation of C-reactive protein and pain following laparoscopic cholecystectomy
Phase 2
- Conditions
- Cholelithiasis.Calculus of gallbladder without cholecystitis
- Registration Number
- IRCT201012115364N1
- Lead Sponsor
- Vice Chancellor for Research & Technology Affairs
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
patients with diagnosis of cholelithiasis who are candidate for laparoscopic cholecystectomy. Exclusion criteria: pregnancy, age under 18 or over 80 years, body mass index over 30, presence of underlying disease, associated infection, history of previous abdominal surgery, diagnosis of empyema of gallbladder, usage of steroids and opioids during last week, and all situations which anesthetic drugs administration is contraindicated in, the selected cases will be enrolled after writing consent.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain intensity. Timepoint: 6 hours, 12 hours and 24 hours after surgery. Method of measurement: visual analog scale (VAS).;Serum Level of CRP. Timepoint: Before surgery and 6, 12 and 24 hours after surgery. Method of measurement: level of serum CRP with Elisa assay.
- Secondary Outcome Measures
Name Time Method Amount of analgesic required. Timepoint: If the patient expressed pain. Method of measurement: miligram.