The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Marywood University
- Enrollment
- 44
- Locations
- 1
- Primary Endpoint
- Vascular function
Study Overview
Brief Summary
The purpose of this study is to examine the effects of resveratrol on health and human performance. The study will evaluate cognitive function and several indicators of physical health before and after taking a resveratrol supplement or a placebo for three weeks.
Detailed Description
Measurements
- blood laboratory parameters
- cognitive assessment changes
- body composition changes
- vascular endothelial response
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Care Provider)
Eligibility Criteria
- Ages
- 45 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •men and women between 45 and 75 years of age
- •Normal heart rate and Blood pressure
- •Ability to use personal computer interface
- •Successful completion of physical activity readiness questionnaire
Exclusion Criteria
- •Cardiovascular disease, uncontrolled hypertension, lung disease
- •inability to tolerate exercise
- •have taken grape related supplement in past 12 months
- •current use of drugs or dietary supplements to enhance exercise performance
- •allergy to wine, grape juice or grape seed supplements
Arms & Interventions
Sugar Pill
Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.
Intervention: Placebo Comparator: Sugar Pill (Other)
Dietary Supplement: resveratrol
Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.
Intervention: resveratrol (Dietary Supplement)
Outcomes
Primary Outcomes
Vascular function
Time Frame: 4 weeks, with option of additional 4 week treatment period
vascular response to stress will be measured using flow mediated dilation and ultrasound.
Secondary Outcomes
- Body fat percentage(4 weeks, with optional additional 4 week treatment period)
- inflammation biomarkers(4 weeks, with optional additional 4 week treatment period)
- cognitive function(4 weeks, with optional additional 4 week treatment period)