*Omega-3 fatty acids in bariatric gastric bypass surgery: effects on liver volume, immune response and erythrocyte function*

Phase 4

Recruiting

• Conditions: excess body weight; Morbid obesity; 10003018; 10017998

• Registration Number: NL-OMON40548
• Lead Sponsor: Medisch Centrum Alkmaar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 62

Inclusion Criteria

•Females undergoing laparoscopic gastric bypass surgery because of morbid obesity
•Age between 18 and 65 years
•Written informed consent
•Patient will fit in the MRI-scan based on waist circumference (less than approx. 150cm and body weight less than 200kg)

Exclusion Criteria

•Pregnancy
•Diabetes mellitus type 1
•Current history of inflammatory, infectious or malignant disease
•The use of anti-inflammatory drugs
•Contra-indications for the use of omega-3 fatty acids
•Patient previously underwent bariatric procedures

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is liver volume after pre-treatment with a low calorie<br /><br>diet compared to pre-treatment with omega-3 fatty acids.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The effect of omega-3 fatty acids on the perioperative immune response and<br /><br>low-grade inflammatory state in adipose tissue.<br /><br><br /><br>The effect of omega-3 fatty acids on the perioperative stress response.<br /><br><br /><br>The effect of omega-3 fatty acids on the function of the red blood cell.<br /><br><br /><br>The effect of gastric bypass surgery on weight, immune response, stress<br /><br>response and red blood cell function.</p><br>