Benefits of systemically administered omega 3 fatty acids on nuclear factor kappa b levels in patients with rheumatoid arthritis and periodontitis .
Not Applicable
- Conditions
- Health Condition 1: K053- Chronic periodontitisHealth Condition 2: M057- Rheumatoid arthritis with rheumatoid factor without organ or systems involvement
- Registration Number
- CTRI/2023/04/051411
- Lead Sponsor
- Panineeya Institute of Dental Sciences and Research centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with Rheumatoid arthritis.
Patients with Chronic periodontitis.
For Periodontitis: 20 teeth should be present with probing pocket depths >= 5mm in one or more sites.
Rheumatoid arthritis patients with Anti-CCP levels Positive for antibodies â?? ( >20u/ml)
Exclusion Criteria
Pregnant and lactating women, Smokers, Patients with any auto immune or systemic disorder other than Rheumatoid arthritis.
Use of Medicines (other than RA medicines) or antibiotics 3 months before the commencement of the study.
History of periodontal treatment within 6 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate if omega-3 fatty acids have beneficial effects in patients with rheumatoid arthritis and periodontitis when used as adjuvant to non surgical periodontal therapyTimepoint: Baseline and 3 months
- Secondary Outcome Measures
Name Time Method Plaque Index(PI), <br/ ><br>Gingival Index (GI) <br/ ><br>Probing pocket depths (PPD)Timepoint: base line and 12 weeks after non surgical periodontal therapy