Correlation of Hepatitis C, Alcoholic Liver Disease, and Renal Failure With Hyperfibrinolysis in Liver Failure

Completed

• Conditions: Cirrhosis
• Interventions: Other: Rotem

• Registration Number: NCT02737345
• Lead Sponsor: Scott Allen

Brief Summary

1. Further characterize the incidence of hyperfibrinolysis in cirrhotics

2. Correlate hyperfibrinolysis with

1. hepatitis C

2. alcoholic liver disease

3. the subset of a\&b with renal failure with and without dialysis

3. Better describe the hyperfibrinolytic ROTEM profile in cirrhotics

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11-01
• Study First Submitted: 2016-04-01
• Study First Submitted QC: 2016-04-12
• Study First Posted: 2016-04-13
• Primary Completion: 2017-04-01
• Study Completion: 2017-04-01
• Status Verified: 2017-11
• Last Update Submitted: 2017-11-06
• Last Update Posted: 2017-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• Be on the the liver transplant waiting list

Exclusion Criteria

• liver failure without eligibility for transplant

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Waiting list	Rotem	Patients on the liver transplant waiting list

Primary Outcome Measures

Name	Time	Method
The percentage of patients who exhibit fibrinolysis	Within 60 minutes of sample run time	The percentage of patients who exhibit fibrinolysis, defined as a decrease in maximum clot firmness \<15% within 60 minutes of sample run time.

Trial Locations

Locations (1)

University of Utah; 🇺🇸 Salt Lake City, Utah, United States