The Contributions of the Multidisciplinary Management of Prosthesis Knee Infections in a Reference Center: A Retrospective Study About 52 Cases.Skin Coverage in a Reference Center: A Retrospective Study About 52 Cases

• Conditions: Knee Joint Prosthesis Infection; Flap Necrosis; Skin Graft Complications
• Interventions: Other: patients having had skin coverage of the knee

• Registration Number: NCT05367726
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Acute and chronic infection of knee joint prosthesis can have several outcomes, the most feared of which is trans-femoral amputation. In order to save the limb while maintaining function, the management of these infections involves several specialists. Orthopedic surgeons are on the front line for carrying out bacteriological samples as well as for changing the material when necessary. The infectiologists coordinate this care by supervising each of the interventions by an antibiotic therapy adapted to the germs and by ensuring the occurrence of adverse events related to the treatment. Plastic surgeons intervene when the skin cover of the knee is deemed to be precarious or when there is an identified loss of substance that could affect the prognosis of the prosthesis. The main objective of our study is to evaluate the success rate of skin coverage and functional recovery for patients cured of their infection. The secondary objective is the identification of risk factors for skin coverage in this population.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2022-05
• Study Start: 2022-05-01
• Study First Submitted: 2022-05-05
• Study First Submitted QC: 2022-05-05
• Last Update Submitted: 2022-05-05
• Study First Posted: 2022-05-10
• Last Update Posted: 2022-05-10
• Primary Completion: 2022-06-01
• Study Completion: 2022-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Patients with a prosthesis knee infection whose management requires skin covering plastic surgery
• Surgical procedures performed at the Croix Rousse Hospital

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Exclusion Criteria

• none

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patients having had skin coverage of the knee	patients having had skin coverage of the knee	patients having had skin coverage of the knee after or at the same time than an orthopedic surgery to treat a knee prosthesis infection

Primary Outcome Measures

Name	Time	Method
rate of patients with prosthesis knee infection requiring skin coverage	2011-2021	proportion of patients with prosthesis knee infection requiring skin coverage amaong all prosthesis knee infection

Secondary Outcome Measures

Name	Time	Method
description of the population at risk of coverage after prosthesis knee infection	2011-2021	rate of failure

Trial Locations

Locations (1)

Hospices Civils de Lyon; 🇫🇷 Lyon, France