Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study

Completed

• Conditions: Borderline Personality Disorder

• Registration Number: NCT04948905
• Lead Sponsor: Centre Hospitalier Universitaire de Nīmes

Brief Summary

One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity. Autobiographical memory is closely linked to the development and maintenance of a coherent, stable sense of self. It enables the individual to understand who he or she is. The investigators hypothesize that individuals diagnosed with Borderline Personality Disorder have a less coherent, stable sense of the self than healthy controls. The aim of the study is therefore to compare the sense of identity between a group of patients diagnosed with Borderline Personality Disorder and a group of healthy individuals (without Borderline Personality Disorder ).

This can be measured by evaluating the content of the self-defining memory using the Self-Defining Memory scale.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-01
• Study First Submitted: 2021-06-17
• Study First Submitted QC: 2021-06-24
• Study First Posted: 2021-07-02
• Primary Completion: 2022-07-31
• Study Completion: 2022-07-31
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-02
• Last Update Posted: 2023-01-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Subject must have given written consent
• Subject affiliated or beneficiary of a health insurance plan.
• Adult subjects between 25 and 55 years of age
• Oral and written mastery of the French language

Inclusion criteria for the borderline group:

• Subject diagnosed as having borderline personality disorder according to the DSM IV classification

Exclusion criteria for the borderline group:

• Patients without diagnosis of borderline personality disorder according to the DSM IV classification after taking the SCID II (Structured Clinical Interview for DSM-III-R Axis II Disorders) test

Exclusion criteria for the control group:

• Subjects considered Borderline after taking the SCID II (Structured Clinical Interview for DSM-III-R Axis II Disorders) test
• Subjects with a score above 8 on the HADS questionnaire corresponding to questionable symptomatology for anxiety and depressive symptoms.

General exclusion Criteria:

• Subjects under court protection, guardianship or curatorship
• Subjects for whom it is impossible to give informed information
• Subjects participating in a Category 1 or 2 RIPH in the 3 months prior to the study
• Subject refusing to give written consent
• Presence of known neurological disease
• Pregnant or breastfeeding women

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sense of Identity in patients diagnosed with Borderline Personality Disorder according to the results of the Self-Defining Memory questionnaire.	Day 7	The answers to the Self-Defining Memory questionnaire will be analyzed. At least 3 memories are asked of the participants. Each memory is rated as follows : On a scale of 0 - 6 for each of the following emotions, participants note how they feel when recalling each memory. Happy, Sad, Angry, Fearful, Surprised, Ashamed,Disgusted,Guilty, Interested, Embarrassed, Contemptful, Proud. 0 = not at all, 3 = Moderately and 6 = Extremely.; Participants must then use the same scale to indicate the vividness and importance of the memory.; They must also note the approximate number of years ago the memory took place (to the nearest whole number).
Sense of Identity in healthy controls according to the results of the Self-Defining Memory questionnaire.	Day 7	The answers to the Self-Defining Memory questionnaire will be analyzed. At least 3 memories are asked of the participants. Each memory is rated as follows : On a scale of 0 - 6 for each of the following emotions, participants note how they feel when recalling each memory. Happy, Sad, Angry, Fearful, Surprised, Ashamed,Disgusted,Guilty, Interested, Embarrassed, Contemptful, Proud. 0 = not at all, 3 = Moderately and 6 = Extremely.; Participants must then use the same scale to indicate the vividness and importance of the memory.; They must also note the approximate number of years ago the memory took place (to the nearest whole number).

Secondary Outcome Measures

Name	Time	Method
Phenomenological details of self-defining memories in patients diagnosed with Borderline Personality Disorder	Day 7	The Memory Characteristics Questionnaire (MCQ) will be used to compare the self-defining memories in each group of patients, Borderline vs. Controls. The MCQ is a self-administered questionnaire for the assessment of phenomenological characteristics of autobiographical memory.; This measurement tool, comprising 15 items and constructed according to a 7-point Likert scale, can distinguish between memories of events, which contain more sensory and contextual details, from memories of contextual details, from memories of imagined events, which contain more elements relating to cognitive operations.
Phenomenological details of self-defining memories in healthy controls	Day 7	The Memory Characteristics Questionnaire (MCQ) will be used to compare the self-defining memories in each group of patients, Borderline vs. Controls. The MCQ is a self-administered questionnaire for the assessment of phenomenological characteristics of autobiographical memory.; This measurement tool, comprising 15 items and constructed according to a 7-point Likert scale, can distinguish between memories of events, which contain more sensory and contextual details, from memories of contextual details, from memories of imagined events, which contain more elements relating to cognitive operations.
Traumas undergone in patients diagnosed with Borderline Personality Disorder: Frequency	Day 7	The Childhood Trauma Questionnaire (CTQ) will be used to evaluate the frequency of traumas undergone by the patient.; The CTQ is a self-administered questionnaire of childhood and adolescent abuse. The short version, validated in French by David P Bernstein in 2003, includes 28 items and gives a quantitative estimate of the severity of maltreatment experienced. This self-administered questionnaire is based on a 5-point Likert scale and covers five main dimensions of abuse: physical abuse, sexual abuse, emotional abuse, physical neglect and emotional neglect.
Traumas undergone in healthy controls: Type	Day 7	The Childhood Trauma Questionnaire (CTQ) will be used to evaluate the type of traumas undergone in healthy controls: The CTQ is a self-administered questionnaire of childhood and adolescent abuse. The short version, validated in French by David P Bernstein in 2003, includes 28 items and gives a quantitative estimate of the severity of maltreatment experienced. This self-administered questionnaire is based on a 5-point Likert scale and covers five main dimensions of abuse: physical abuse, sexual abuse, emotional abuse, physical neglect and emotional neglect.
Self-coherence of self-defining memories in patients diagnosed with Borderline Personality Disorder	Day 7	The TALE (Thinking About Life Experiences) self-questionnaire will be used to evaluate this point. This questionnaire contains 15 items, each to be answered with a 5-point Lickert scale (1 = almost never, 5 = very frequently) with the aim of measuring 3 theoretical functions found in the autobiographic memory: * The self-continuity function; * The social bonding function; * The directing behavior function
Self-coherence of self-defining memories in healthy controls	Day 7	The TALE (Thinking About Life Experiences) self-questionnaire will be used to evaluate this point. This questionnaire contains 15 items, each to be answered with a 5-point Lickert scale (1 = almost never, 5 = very frequently) with the aim of measuring 3 theoretical functions found in the autobiographic memory: * The self-continuity function; * The social bonding function; * The directing behavior function
Traumas undergone in healthy controls: Frequency	Day 7	The Childhood Trauma Questionnaire (CTQ) will be used to evaluate the frequency of traumas undergone by healthy controls.; The CTQ is a self-administered questionnaire of childhood and adolescent abuse. The short version, validated in French (David P Bernstein et al. 2003), includes 28 items and gives a quantitative estimate of the severity of maltreatment experienced. This self-administered questionnaire is based on a 5-point Likert scale and covers five main dimensions of abuse: physical abuse, sexual abuse, emotional abuse, physical neglect and emotional neglect.
Traumas undergone in patients diagnosed with Borderline Personality Disorder: Type	Day 7	The Childhood Trauma Questionnaire (CTQ) will be used to evaluate the type of traumas undergone by the patient.; The CTQ is a self-administered questionnaire of childhood and adolescent abuse. The short version, validated in French, includes 28 items and gives a quantitative estimate of the severity of maltreatment experienced. This self-administered questionnaire is based on a 5-point Likert scale and covers five main dimensions of abuse: physical abuse, sexual abuse, emotional abuse, physical neglect and emotional neglect.

Trial Locations

Locations (1)

Nîmes University Hospital; 🇫🇷 Nîmes, Gard, France