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临床试验/CTRI/2022/11/047748
CTRI/2022/11/047748招募中2 期

A PROSPECTIVE STUDY TO ASSESS THE EFFECT OF HOMOEOPATHIC TREATMENT IN THE MANAGEMENT OF ENDOMETRIOSIS

PONNU C1 个研究点 分布在 1 个国家目标入组 33 人开始时间: 2022年3月12日最近更新:

试验速览

阶段
2 期
状态
招募中
发起方
入组人数
33
试验地点
1
主要终点
Changes in Endometriosis Health Profile questionnaire score before and after Homoeopathic treatment of Endometriosis

研究概览

简要总结

Presence of functioning endometrium in sites other than uterine mucosa is called endometriosis. These islands of endometriosis are composed of endometrial glands surrounded by endometrial stroma, and are capable of responding to a varying degree to cyclical hormonal stimulation. Endometriosis is a disease of contrast. It is a benign but it is locally invasive, disseminates widely. Cyclic hormones stimulate growth but continuous hormone suppress it.

The occurrences of endometriosis are genetic, multifactorial, vaginal or cervical atresia encouraging retrograde spill. The more frequent the cycles and more the bleeding, greater is  the risk of endometriosis. Risk factors are polymenorrhagia, retroverted uterus, which increases the risk of retrograde spill.

The common site of endometriosis are ovaries, the pouch of Douglas, including the utereosacral ligaments, peritoneum overlying the bladder, sigmoid colon, back of uterus, ovarian fossa, intestinal coils and appendix. Endometriosis is seen in the umbilicus following an operation, in laparotomy scar, in tubal stumps following sterilization operation, in amputated stumps of the cervix and in the scars  of the vulva and perineum.

Symptoms include  Dysmenorrhoea, Adominal pain, Dyspareunia, Infertility, Menstrual symptoms, Chronic pelvic pain, Urological and bowel symptoms.

RATIONALE OF STUDY

Endometriosis is a common gynaecological condition affecting 2-10% of women of childbearing age. At present, there is no known way to prevent endometriosis. Enhanced awareness, followed by early diagnosis and management may slow or halt the natural progression of the disease and reduce the long-term burden of its symptoms, including possibly the risk of central nervous system pain sensitisation, but currently there is no cure.

Usual allopathic treatment include hormone therapy and minimal invasive surgery. Hormone therapy suppresses endometriosis for the duration of therapy, it does not prevent recurrence. Moreover, hormone delay pregnancy by their contraceptive effect, beside the drugs being expensive. Weight gain, irregular bleeding, reduced libido, mental depression are other side effect

Homoeopathy being a holistic system of medicine has a better scope in the management of endometriosis; a constitutional approach can be adopted in homeopathy. Previous studies on the role of homeopathy in treating endometriosis are also limited. Homoeopathy is cost effective; prevent recurrence and has no side effects. Thus, this study focuses on the usefulness of homeopathic medicines in the management of endometriosis

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
Female

入选标准

  • •Patients with symptoms and signs of endometriosis •Female, 20-60 years old •Cases fulfilling the examination findings and transvaginal USG finding.

排除标准

  • 1.Asymptomatic case of endometriosis 2.Complicated endometriosis cases requiring surgery 3.Cases with psychiatric illness 4.Any active malignancy.

结局指标

主要结局

Changes in Endometriosis Health Profile questionnaire score before and after Homoeopathic treatment of Endometriosis

时间窗: 1 YEAR

Changes in Marinoff dyspareunia scale before and after Homoeopathic treatment of Endometriosis

时间窗: 1 YEAR

Changes in transvaginal USG findings before and after Homoeopathic treatment of Endometriosis

时间窗: 1 YEAR

次要结局

  • Changes in Marinoff dyspareunia scale before and after Homoeopathic treatment of Endometriosis(Changes in Endometriosis Health Profile questionnaire score before and after Homoeopathic treatment of Endometriosis)

研究者

发起方
PONNU C
申办方类型
Other [self]

研究点 (1)

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