Restoration vs. Compensation in Neurovisual Rehabilitation of Visual Field Defects

Phase 2

Completed

• Conditions: Hemianopia; Brain Injuries, Traumatic
• Interventions: Behavioral: Vision Restoration Training (VRT); Behavioral: Vision Exploration Training (VET)

• Registration Number: NCT04043429
• Lead Sponsor: University of Magdeburg

Brief Summary

Visual field defects (VFD) are a frequent effect of cerebral lesions especially after posterior cerebral artery stroke. The present study was conducted to compare effects of vision restoration training (VRT) and compensation training (Visual Exploration Training, VET) on visual field performance.

Detailed Description

Not available

Study Timeline

• Study Start: 2003-01
• Primary Completion: 2005-01
• Study Completion: 2005-01
• Study First Submitted: 2014-09-18
• Status Verified: 2019-07
• Study First Submitted QC: 2019-07-31
• Last Update Submitted: 2019-07-31
• Study First Posted: 2019-08-02
• Last Update Posted: 2019-08-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

• Visual field defects after brain damage
• lesion age above 6 months
• documented brain lesions due to ischemic stroke, hemorrhage or tumor demonstrated by computer tomography or by magnet resonance imaging

Exclusion Criteria

• hemispatial neglect
• complete blindness
• severe psychotic diseases
• serious drug abuse
• chronic degenerative diseases (dementia, multiple sclerosis)
• severe motor impairments
• noticeable low intelligence influencing proper comprehension of diagnostic and training instructions
• considerable impaired vision (visual acuity below 0.1 generated by amblyopia, opacity of cornea or lens, maculopathy and other retinal diseases where vision impairment is expected in the next month (e.g. subretinal neovascularisation, retinitis pigmentosa, diabetic retinopathy)
• inability to fixate due to central scotoma, pathological nystagmus or other forms of fixation disabilities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Vision Restoration Training (VRT)	Vision Restoration Training (VRT)	home-based rehabilitation program which applies intense light stimulation via a PC-monitor to areas of residual vision with a duration of 1 hour daily/six days a week, subjects are asked to respond via button press upon appearance of light stimuli without eye movements
Vision Exploration Training (VET)	Vision Exploration Training (VET)	home-based rehabilitation program to train eye movements upon visual stimuli presented via a PC-monitor with a duration of 1 hour daily/six days a week, subjects are asked to shift their gaze towards targets and respond via button press upon detection of targets

Primary Outcome Measures

Name	Time	Method
Humphrey Field Analyzer (Static Perimetry) - Detectection performance change before vs. after training (%)	3 months
High Resolution Perimetry - Detectection performance change before vs. after training (%)	3 months

Trial Locations

Locations (1)

Inst. f. Medical Psychology, Univ. of Magdeburg; 🇩🇪 Magdeburg, Germany