Down syndrome's estimated glomerular filtration rate trial
- Conditions
- D004314Down syndrome
- Registration Number
- JPRN-jRCT1030220054
- Lead Sponsor
- ishino Tomohiko
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 15
Children with Down syndrome between the ages of 2 and 18 years who had their inulin clearance measured at our facility.
Children who gave consent for this study.
1) Abnormally low (less than 0.5) or abnormally high (greater than 0.5) ratio of urinary inulin excretion to blood inulin concentration
2) GFR greater than 150 ml/min/1.73m2
3) Patients who have had surgery for congenital heart disease or are expected to have surgery in the future
4) Patients with severe renal dysfunction (anuria, oliguria, on dialysis)
5) Respiratory failure or heart failure requiring oxygen administration
6) Patients undergoing treatment for gastrointestinal symptoms or common cold symptoms
7) Women who are pregnant, may become pregnant, or who are breast-feeding
8) Patients with neurological disorders taking antiepileptic drugs
9) Complications of chromosomal or genetic abnormalities other than Down syndrome
10) If the doctor in charge judges that the patient is inappropriate to participate in this trial
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method