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临床试验/JPRN-jRCT1032230398
JPRN-jRCT1032230398尚未招募Unknown

Influence of mechanical ventilation settings on breath-by-breath exhaled propofol concentration during general anesthesia: a pharmacokinetic study

Masui Kenichi0 个研究点目标入组 30 人开始时间: 2023年10月16日最近更新:
适应症

试验速览

阶段
Unknown
状态
尚未招募
发起方
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
>= 18age old 至 ot applicable(—)
性别
All

入选标准

  • 1) 30 scheduled surgery patients aged 18 and over who are hospitalized at Yokohama City University
  • Hospital (10 aged 18-49, 10 aged 50-69, 10 aged 70 and over. 5 males and 5 females in each age group)
  • 2) Patients who are expected to undergo general anesthesia for more than 3 hours
  • 3) Supine position, general anesthesia patient under double lung ventilation
  • 4) Patients undergoing invasive arterial pressure catheter insertion
  • 5) Patients who have given their written consent to participate in this study

排除标准

  • 1) Patients contraindicated for administration of propofol
  • 2) Patients whose ASA classification, which is the general condition classification of the American Society of Anesthesiologists, is class 4 or higher
  • 3) Surgery with head low or high at 25 degrees or more
  • 4) Patients with interstitial pneumonia, COPD, pulmonary edema, severe cardiac dysfunction, severe liver
  • dysfunction
  • 5) Pregnant women (lactating women)

研究者

发起方
Masui Kenichi

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