JPRN-jRCT1032230398
Not yet recruiting
未知
Influence of mechanical ventilation settings on breath-by-breath exhaled propofol concentration during general anesthesia: a pharmacokinetic study
Masui Kenichi0 sites30 target enrollmentOctober 16, 2023
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Elective surgical procedure
- Sponsor
- Masui Kenichi
- Enrollment
- 30
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) 30 scheduled surgery patients aged 18 and over who are hospitalized at Yokohama City University
- •Hospital (10 aged 18\-49, 10 aged 50\-69, 10 aged 70 and over. 5 males and 5 females in each age group)
- •2\) Patients who are expected to undergo general anesthesia for more than 3 hours
- •3\) Supine position, general anesthesia patient under double lung ventilation
- •4\) Patients undergoing invasive arterial pressure catheter insertion
- •5\) Patients who have given their written consent to participate in this study
Exclusion Criteria
- •1\) Patients contraindicated for administration of propofol
- •2\) Patients whose ASA classification, which is the general condition classification of the American Society of Anesthesiologists, is class 4 or higher
- •3\) Surgery with head low or high at 25 degrees or more
- •4\) Patients with interstitial pneumonia, COPD, pulmonary edema, severe cardiac dysfunction, severe liver
- •dysfunction
- •5\) Pregnant women (lactating women)
Outcomes
Primary Outcomes
Not specified
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