To detect and to compare diabetic biomarker in saliva and blood of Periodontitis patients with and without Type 2 Diabetes Mellitus
- Conditions
- Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications
- Registration Number
- CTRI/2023/02/049363
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Presence of minimum 20 natural teeth. Group 1 Patients diagnosed with Generalized periodontitis and Type 2 Diabetes Mellitus. Group 2 Patients diagnosed with Generalized Periodontitis who are normoglycemic. Group 3 Healthy controls.
1 Patients with any other systemic disease accompanying Type 2 DM.
2 Patients with Type 1 DM.
3 Patients who are obese (BMI >30)
4 Current or former smokers.
5 Pregnant women.
6 Patients with any intra oral lesions and unrestored caries.
7 Patients with history of periodontal therapy within past 6 months.
8 Patients with history of antibiotic intake within past 3 months.
9 Patients with history of anti-inflammatory drug therapy within 3 months.
10 Patients taking any others medications excluding medication for DM.
11 Patients taking SGLT-2 inhibitor (SGLT-2i treatment can interfere with the
measurement of 1,5-AHG, resulting in a falsely low value in patients with
controlled blood glucose levels).
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method