Effect of Esketamine on Anxiety State in Patients Undergoing Abdominal Tumor Surgery

Not Applicable

Recruiting

• Conditions: Anxiety State; Esketamine

• Registration Number: NCT06530706
• Lead Sponsor: Zhejiang Cancer Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-7-29
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Inclusion Criteria:<br><br> - Patients undergoing abdominal tumor surgery;<br><br> - older than 18 years old and younger than 70 years old;<br><br> - ASA grade I-III;<br><br> - Hamilton anxiety scale = 8.<br><br>Exclusion Criteria:<br><br> - Having serious mental illness before surgery or on antipsychotic medication at the<br> time of surgery;<br><br> - Severe organ function lesions such as heart failure (left ventricular ejection<br> fraction <30%), myocardial infarction, kidney failure (requiring kidney replacement<br> therapy), liver function impairment (Child-Pugh grade C), etc.<br><br> - Patients arranged to receive general anesthesia combined with epidural anesthesia<br> patients;<br><br> - Patients who cannot communicate, read or write due to visual, auditory, language or<br> other reasons;<br><br> - Patients allergic to ketamine;<br><br> - Patients refused to use postoperative self-controlled intravenous analgesia pump;<br><br> - Patients refused to participate in the study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Whether esketamine can reduce anxiety status in patients with anxiety

Secondary Outcome Measures

Name	Time	Method
To explore whether esketamine can improve sleep status;To explore whether esketamine can improve life quality