Effect of a single low-dose dose of esketamine on postpartum depression and quality of recovery in women undergoing cesarean section: a prospective, randomised controlled study
Not Applicable
- Conditions
- N/A
- Registration Number
- ChiCTR2400088992
- Lead Sponsor
- Dongguan Maternal and Child Health Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
Inclusion Criteria <br>1. ASA classification I-II; Full term singleton mothers<br>2. Age range of 18 to 60 years old;<br>3. Body mass index (BMI) 18~35kg/m2;<br>4. Patients undergoing elective cesarean section with a surgical duration of less than 2 hours;<br>5. Capable of signing informed consent forms and willing to accept relevant treatment plans
Exclusion Criteria
- Individuals with contraindications for intraspinal puncture; Failure of spinal anesthesia;<br>2. History of long-term use of analgesics, sedatives, and anti anxiety drugs;<br>3. Hypertension, diabetes, hyperthyroidism, hypothyroidism, etc. before pregnancy;<br>4. Known individuals who are allergic to the experimental drug<br>5. Patients with communication barriers, cognitive impairment, and a history of mental illness;<br>6. There are other situations where researchers believe it is not appropriate to participate in this study
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Edinburgh Postnatal Depression Scale (EPDS) scores on the 2nd and 7th day postpartum;
- Secondary Outcome Measures
Name Time Method Postpartum Recovery Quality Score (ObsQoR-10) at 24 and 48 hours postpartum;Resting and exercise pain score (VAS) 24 hours postpartum;Postpartum hospitalization duration;