The Effectiveness of Lorazepam for Anxiety and Postoperative Pain Reduction in outpatient Third Molar Surgery (Split Mouth Technique)
- Conditions
- Outpatient third molar surgery who has mild to moderate anxiety.Anxiety, pain, Lorazepam, placebo
- Registration Number
- TCTR20231109001
- Lead Sponsor
- Ministry of Higher Education, Science, Research, Research and innovation, Prince of Songkla University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
1. ASA classification I, II
2. Age between 18-30 years old
3. Thai patient
4. Need Lower third molar surgery on both sides
5. Impacted tooth difficulty level 5-7 points ( Pederson's difficulty index)
6 . Corah's Dental Anxiety Scale Revised (DAS-R) equal or more than 12 (mild to moderate)
7. Available appointment in the morning
1. The patient who has an anaphylactic reaction to Lorazepam, other Benzodiazepines, Ibuprofen and tramadol or other medications that interact with Lorazepam.
2. The patient with systemic disease consists of severe respiratory impairment, acute narrow-angle glaucoma, sleep apnea, psychosis, liver disease and kidney disease
3. Patients with a history of alcohol dependence and abuse
4. Patient with pregnancy
5. Patient with pericoronitis
6. loss follow up
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anxiety score the day before operation day, operation day (before and after operation time) Corah's dental anxiety scale
- Secondary Outcome Measures
Name Time Method Anxiety score After finishing third molar surgery 2,3,4,6,8 hr Visual Analogue Scale