The Effect of Perioperative Factors on Postoperative Outcomes After Lung Transplantation

Recruiting

• Conditions: Postoperative Complications After Lung Transplantation

• Registration Number: NCT06603350
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

1. Evaluate the influence of perioperative factors on postoperative outcomes in patients undergoing lung transplantation patients.

2. To evaluate the feasibility of using pulmonary ultrasound to identify lung complications such as atelectasis and pulmonary edema after lung transplantation

3. Observe the changes of perioperative inflammation and immune indexes after lung transplantation

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-07
• Study Start: 2024-07-28
• Study First Submitted: 2024-09-05
• Study First Submitted QC: 2024-09-17
• Last Update Submitted: 2024-09-17
• Study First Posted: 2024-09-19
• Last Update Posted: 2024-09-19
• Primary Completion: 2026-02
• Study Completion: 2026-08

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Prosedure of lung transplantation, Aged more than 18 years old

Exclusion Criteria

Secondary lung transplantation, multiple organ transplantation, refusal to participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative pulmonary complications	3 days after surgery	Incidence of atelectasis and primary graft dysfunction(PGD) detcted by lung ultrasound
Mortality	1 year after surgery	Survival rate after lung transplantation

Secondary Outcome Measures

Name	Time	Method
Inflammatory index IL-6	3 days after after surgery	Variation of perioperative inflammatory index IL-6

Trial Locations

Locations (1)

Department of Anesthesiology, Second Affiliated Hospital, Zhejiang University School of Medicine; 🇨🇳 Hangzhou, Zhejiang, China