NL-OMON44899已完成不适用
Differentiated thyroid carcinoma in children: Late effects of treatment and pathophysiological background in the Netherlands - DTC in children
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 160
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 2 至 99（—）
入选标准
- •Differentiated thyroid carcinoma diagnosed between 1970 and 2013 at age <= 18 years and treated in the Netherlands.
排除标准
- •Not applicable for the study in its entirety because analysis of somatic mutations will be performed in all patients. Late effects are defined as effects occurring >= 5 years after diagnosis. So, evaluation of late effects will only be performed in 5-year survivors. ;Therefore, exclusion criteria are applicable for the following parts of the study:
- •A. Evaluation late effects including quality of life:
- •- <5 years since diagnosis
- •- DTC as a second malignancy
- •- Thyroid hormone withdrawal or rhTSH <3 months before evaluation;B. In addition to A, for semen analysis:
- •- Use of drugs that interact with semen quality
- •- Use of anabolic steroids
- •- Fever (body temperature >38°C) in the three months before semen analysis;C. In addition to A, for evaluation quality of life:
- •- Not fluent in Dutch;An exhaustive account based on the inclusion- and exclusioncriteria is provided below 'Aanvullende opmerkingen' ('Additional remarks').
研究者
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