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Neurophysiologic Effects of Cervical Spinal Manipulation in Asymptomatic Individuals

Not Applicable
Completed
Conditions
Healthy Subjects
Interventions
Other: Cervical spine mechanical manipulation
Other: Cervical spine manual manipulation
Other: Placebo intervention
Registration Number
NCT03463343
Lead Sponsor
Escola Superior de Tecnologia da Saúde do Porto
Brief Summary

This study had the goal of analyse the neurophysiologic effects of both mechanical and manual cervical manipulation, in asymptomatic individuals.

Detailed Description

In this study, the investigators compared the effects of manual manipulation and instrument assisted manipulation of C3/C4 on muscle tone, elasticity and stiffness and on pressure pain threshold , and pressure pain perception. The muscles evaluated were upper trapezius and biceps brachialis, bilaterally. The study also had a placebo and a control group. All individuals were asymptomatic.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
59
Inclusion Criteria
  • Healthy subjects.
  • Minimum of 18 years old.
Exclusion Criteria
  • Pain in cervical region, shoulders or arms.
  • History of trauma or disease in the cervical region or upper limb.
  • Use of medication that could affect the outcomes (painkillers, NSAID, or anti depressives) during the last week.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Mechanical manipulationCervical spine mechanical manipulationIn the Mechanical manipulation group, the Activator instrument was applied on the right transverse apophyses of C3.
Manual manipulationCervical spine manual manipulationIn the Manual manipulation group, the thrust was applied in the right side of C3/C4 with neutral flexion/extension, ipsilateral side bending and contralateral rotation. Then, a low amplitude, high velocity thrust in rotation was delivered.
PlaceboPlacebo interventionThe subjects were positioned in the same pre-manipulative position as the manual manipulation group, but the thrust didn't occur. Instead, the position was hold for 3 seconds and then the subject's head returned passively to neutral position.
Primary Outcome Measures
NameTimeMethod
Pressure pain thresholdsImmediately after the intervention

To measure the pressure pain threshold, it was used an electronic pressure dynamometer FORCE ONE™ FDIX (Wagner Instruments - Greenwich, USA), with 1cm2 of surface. The values were expressed in Kg/cm2. The pressure was increased at a rate of 1 kg/cm2/s until the subject inform that the sense of pressure has become a sense of pain.

Pressure pain perceptionImmediately after the intervention

To evaluate the pressure pain perception, it was used a Visual Analogue Scale (VAS). The pressure increased until 2,5 kg/cm2 and was hold for 5 seconds, and the subject used the VAS scale to record the pressure pain perception he felt.

Secondary Outcome Measures
NameTimeMethod
Muscle toneImmediately after the intervention

To measure muscle tone it was used the MyotonPro device. It was used to evaluate those parameters both on the biceps and on the upper trapezius, bilaterally. The device was located perpendicular to the middle point of each muscle and it were recorded 6 impulses in each one of them. The non-neural tone was recorded as frequency.

Muscle stiffnessImmediately after the intervention

To measure muscle stiffness it was used the MyotonPro device. It was used to evaluate this parameter both on the biceps and on the upper trapezius, bilaterally. The device was located perpendicular to the middle point of each muscle and it were recorded 6 impulses in each one of them. The muscle stiffness was recorded as N/m.

Muscle elasticityImmediately after the intervention

To measure muscle elasticity it was used the MyotonPro device. It was used to evaluate those parameters both on the biceps and on the upper trapezius, bilaterally. The device was located perpendicular to the middle point of each muscle and it were recorded 6 impulses in each one of them. The elasticity was indicated by logarithmic decrement.

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