Impact of Text Message Reminders on Immunosuppressive Medication Adherence Among Kidney Transplant Recipients: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- The effect of sending reminder text messages on immunosuppressive medication adherence
研究概览
简要总结
Aims and Objective: The study aimed to assess the impact of text message reminders on medication adherence among kidney transplant recipients.
Background: One of the most common problems encountered in transplant patients is incompatibility with immunosuppressive drugs, one of the most important reasons for graft rejection.
Design: A randomized controlled trial was conducted from January to October 2021 and conducted in accordance with the Consolidated Standards of Reporting Trials 2010 guidelines.
Methods: This randomized controlled trial included a total of 100 patients receiving a kidney transplant, 50 in the intervention group and 50 in the control group. Patients in the intervention group were sent text message reminders four times a day during the 6th to 9th months after transplantation. Control patients received no such intervention. Tacrolimus concentrations in the bloodstream were monitored for all participants through measurements taken at months 7,8, and 9. Data collection tools included Sociodemographic and Descriptive Characteristics Form and Immunosuppressive Medication Adherence Scale.
Research hypotheses H1- Sending text message reminders improves immunosuppressive medication adherence in kidney transplant recipients.
H2- Utilization of text messages as reminders has a significant influence on tacrolimus blood profiles in kidney transplant recipients.
H3- There is a correlation between the scores from the Immunosuppressive Medication Adherence Scale and mean tacrolimus plasma levels in kidney transplant recipients.
H4- There is a correlation between the sociodemographic and descriptive characteristics of kidney transplant recipients and their mean scores from the Immunosuppressive Medication Adherence Scale.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years or older
- •Being a recipient of a kidney transplant for the first time
- •Being a kidney transplant recipient at post-transplant month 6 with scheduled follow-up until month 9
- •Ongoing immunosuppressive drug therapy
- •Absence of any disability that hinders communication
- •No diagnosis of psychological and mental problems
- •Being an active cell phone user
- •Ability to read and write
- •Voluntary participation in the research.
排除标准
- •Hospitalization for any reason during the research period
- •History of combined or dual organ transplantation.
结局指标
主要结局
The effect of sending reminder text messages on immunosuppressive medication adherence
时间窗: baseline and 9 months
The IMAS is a validated an 11-item self-report questionnaire developed in 2015 to measure medication adherence in patients that have received solid organ transplants and are prescribed immunosuppressive drugs.
次要结局
未报告次要终点
研究者
Kübra Erdal
Nurse
Akdeniz University Hospital