Comparison Between Tuberculin Vaccine and Cryotherapy in the Treatment of Genital Wart Patients
试验速览
- 阶段
- 3 期
- 入组人数
- 45
- 主要终点
- number of patients with complete resolution of genital warts
研究概览
简要总结
Cutaneous and genital warts are common dermatological conditions caused by Human Papilloma Virus. Although it is a benign condition it causes disfigurement, has tendency to collect, can be transmitted to others, this makes adequate and timely treatment important, while many warts are resolve spontaneously over several years, most patients seek treatment because the warts are unsightly and often tender or painful.
详细描述
Genital warts are highly contagious sexually transmitted diseases (STD) caused by infection of Human Papilloma Virus and, as the most common STD in developed countries, can currently be considered to be globally epidemic.
It is estimated that the frequency of Human Papilloma Virus infection among women in the world ranges from 2% to 44%.
The conventional modalities in treatment of warts include destructive therapies such as salicylic acid, trichloroacetic acid, cryotherapy, silver nitrate, phenol, cantharidin, surgical interventions and laser, antiproliferative agents such as bleomycin, vitamin D analogs, podophyllin, 5 fluorouracil and antiviral agents such as cidofovir and retinoids.
There are different mechanisms have been proposed for the resolution of warts with skin test antigens such as mumps, candida, trichophyton both at the injected as well as distant sites.
Tuberculin:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All types of genital and anal warts will be included in this study especially patients with 5 or more warts and more than 1 cm in size
排除标准
- •Patients with immunodeficient diseases or receiving any immunosuppressive drugs
- •Pregnancy and lactation
结局指标
主要结局
number of patients with complete resolution of genital warts
时间窗: 4 months
frequency (number)
次要结局
未报告次要终点
研究者
Mena Ramsis Haleem
Principal Investigator
Assiut University