Non-Nicotine Agents for Smoking Cessation
Phase 3
Completed
- Conditions
- Tobacco Use Disorder
- Registration Number
- NCT00108537
- Lead Sponsor
- US Department of Veterans Affairs
- Brief Summary
The primary objective of this study is to determine which is the better approach to smoking cessation in veterans: bupropion combined with transdermal nicotine or high dose nicotine replacement therapy (NRT) using transdermal nicotine combined with nicotine inhaler.
- Detailed Description
This study is a two-arm open-label, randomized controlled trial of bupropion combined with transdermal nicotine versus high dose NRT (transdermal nicotine and nicotine inhaler) with all subjects receiving a behavioral counseling program for smoking cessation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Readiness to set a quit date in the next two weeks,
- Current smoking of at least 15 cigarettes a day
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Exclusion Criteria
- Current untreated depression or receiving treatment for depression,
- History of seizures, major head injury, or other predisposition for seizures
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Denver VA Medical Center
🇺🇸Denver, Colorado, United States