'Photo-allergic contact dermatitis from cinnamon and cinnamon-derivatives'

Conditions: allergy to cinnamon (-derivatives)
10001708
10014982

Registration Number: NL-OMON29735

Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 100

Inclusion Criteria

Patients with a known cinnamon (-derivatives) allergy
Patients with a positive fragrance patch test (fragrance mix 1 and/or fragrance mix 2)
Age 18 years and above
Written informed consent
Skin to be tested has been clinical normal for the preceding two weeks

Exclusion Criteria

Pregnant women
Topical therapy at skin to be tested in previous two weeks
Lotions and commercial skin treatments on skin to be tested in less than 24 hours
Previous (2 weeks) sun exposition at skin to be tested

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Regarding the literature we expect that concomitant reactions or<br /><br>cross-reactivity between cinnamon (-derivatives) and cinnamon-derived UV<br /><br>protectors will occur. If we detect this association between<br /><br>cinnamon-derivatives allergy and UV protectors, we expect the finding to be of<br /><br>important clinical relevance. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Frequency of allergy for cinnamon, cinnamon-derivatives and fragrance in the<br /><br>study population.<br /><br>Presence and/or absence of cross-reactivity and concomitancy among<br /><br>cinnamon(-derivatives) and cinnamon derived UV protectors. </p><br>