CTRI/2018/02/012076尚未招募未知
A Prospective Randomized study to compare the efficacy of Propofol-Ketamine combination with Dexmedetomidine for performing Drug Induced Sleep Endoscopy(DISE) in patients of Obstructive Sleep Apnoea.
TATA Motors Hospital0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •All patients who give their informed consent willingly.
- •Clinical symptoms of snoring, morning headaches,tiredness,daytime sleepiness.
- •ASA status 1-2.
- •Apnoea-Hypopnea Index (AHI) score greater than 5 events per hour on Polysomnography.
- •No active focus of infection in nose and throat.
- •All patients who have previously failed to respond to conservative treatment for OSA, like changes in sleep position and sleep hygiene.
- •Patients who were either intolerant or unwillingly to use continuous positive airway pressure therapy.
- •Patients with no major systemic disease.
排除标准
- •Age < 18 years and >60 years.
- •Patients with high ASA score >3.
- •Severe OSA (AHI >70 events/hour).
- •Morbid Obesity BMI >30kg/m2.
- •Patients with 2nd-3rd degree A-V block.
- •Known allergies against the study drugs.
- •Gross maxillary and mandibular deformities (mainly retrognathia) on lateral cephalometry.
- •Patients with psychiatric disorders.
- •Patients who have undergone previous surgical therapies for OSA.
- •Mallampati score of 3-4.
- •History of drug or alcohol abuse.
- •History of chronic alcohol use.
研究者
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